WHF Lab

Liu M, Huang K, Zhang J, Li Q, Wang X, Gu B, Tang H, Du Z, Hu L, Qi S, Ma Y, Yu H, Xie W*, Fang X*, Wang H*. CRISPR live-cell imaging reveals chromatin dynamics and enhancer interactions at multiple non-repetitive loci Nature Biotechnology, 2025. Read Online

Chen Q, Wang S, Zhang J, Xie M, Lu B, He J, Zhen Z, Li J, Zhu J, Li R, Li P, Wang H, Vakoc C, Roeder R*, Chen M*. JMJD1C forms condensate to facilitate a RUNX1-dependent gene expression program shared by multiple types of AML cells Protein & Cell, 2025 16-5, 338-364. Read Online

Du Z, Hu L, Zou Z, Liu M, Li Z, Lu X, Harris C, Xiang Y, Chen F, Yu G, Xu K, Kong F, Xu Q, Huang B, Liu L, Fan Q, Wang H*, Kalantry S*, Xie W*. Stepwise de novo establishment of inactive X chromosome architecture in early development Nature Genetics, 2024 56, 2185–2198. Read Online

Yang L, Min Y, Liu Y, Gao B, Liu X, Huang Y, Wang H, Yang L, Liu Z, Chen L*. CRISPR-array-mediated imaging of non-repetitive and multiplex genomic loci in living cells, Nature Methods, 2024 21, 1646–1657. Read Online

Zhang Z, Rong X, Xie T, Li Z, Song H, Zhen S, Wang H, Wu J, Jaffrey S, Li X*. Fluorogenic CRISPR for genomic DNA imaging, Nature Communications, 2024 15, 934. Read Online

Li Q, Gao Y, Wang H*. CRISPR-Based Tools for Fighting Rare Diseases, Life, 2022 Nov 24;12(12):1968. Read Online

Lin X, Liu Y, Liu S, Zhu X, Wu L, Zhu Y, Zhao D, Xu X, Chemparathy A, Wang H, Cao Y, Nakamura M, Noordermeer JN, La Russa M, Wong WH, Zhao K, Qi LS*. Nested epistasis enhancer networks for robust genome regulation, Science, 2022 Aug 11;Vol 377, Issue 6610, pp. 1077-1085. Read Online

Wang H, Han M, Qi LS, Engineering 3D genome organization, Nature Reviews Genetics, 2021 Feb; PMID: 33558716 Read Online

Wang H, Nakamura M, Abbott TR, Zhao D, Luo K, Yu C, Nguyen CM, Lo A, Daley PT, La Russa M, Liu Y, Qi LS, CRISPR-mediated live imaging of genome editing and transcription. Science, 2019 Sep; Vol. 365, Issue 6459, pp. 1301-1305. Read Online

Wang H, Xu X, Nguyen CM, Liu Y, Gao Y, Lin X, Daley PT, Kipniss NH, La Russa M, Qi LS, CRISPR-Mediated Programmable 3D Genome Positioning and Nuclear Organization. Cell, 2018 Oct; 175, 1405-1417 e1414. Read Online

Liu Y, Yu C, Daley T, Wang H, Cao W, Lin X, Still C, Bhate S, Liu H, Zhao D, Wang H, Xie X, Ding S, Wong WH, Wernig M, Qi LS, CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming. Cell Stem Cell, 2018 Nov; 23(5):758-771.e8. Read Online

Kipniss N, Dingal PCD, Abbott T, Gao Y, Wang H, Dominguez A, and Labanieh L, Qi LS, Engineering Cell Sensing and Responses Using a GPCR-Coupled CRISPR-Cas System. Nature Communications, 2017 Dec; 2212. Read Online

Wang H, La Russa M, Qi LS, CRISPR-Cas9 in genome editing and beyond. The Annual Review of Biochemistry, 2016 Aug; Vol. 85: 227-264. Read Online

Wang H, Brust-Mascher I and Scholey JM, The microtubule cross-linker Feo controls the midzone stability, motor composition, and elongation of the anaphase B spindle in Drosophila embryos. Molecular Biology of the Cell. 2015 Apr 15; 26(8):1452-62. PMID: 25694445.Selected as the Cover paper. Read Online

Wang H, Brust-Mascher I and Scholey JM, Sliding filaments and mitotic spindle organization, Nature Cell Biology, 2014 Aug; 16(8):737-739. PMID: 25082196 Read Online

Wang H, Brust-Mascher I, Civelekoglu-Scholey G and Scholey JM, Patronin mediates a switch from kinesin-13-dependent poleward flux to anaphase B spindle elongation, Journal of Cell Biology, 2013 Oct; 203(1):35-46. PMCID: PMC3798244. Read Online